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dc.contributor.author Ayala, Diego
dc.contributor.author Guerrero, Rafael F.
dc.contributor.author Kirkpatrick, Mark
dc.coverage.spatial Cameroon
dc.date.accessioned 2012-10-12T19:43:08Z
dc.date.available 2012-10-12T19:43:08Z
dc.date.issued 2012-11-28
dc.identifier doi:10.5061/dryad.k94p3
dc.identifier.citation Ayala D, Guerrero RF, Kirkpatrick M (2012) Reproductive isolation and local adaptation quantified for a chromosome inversion in a malaria mosquito. Evolution 67(4): 946-958.
dc.identifier.uri http://hdl.handle.net/10255/dryad.43127
dc.description Chromosome inversions have long been thought to be involved in speciation and local adaptation. We have little quantitative information, however, about the effects that inversion polymorphisms have on reproductive isolation and viability. Here we provide the first estimates from any organism for the total amount of reproductive isolation associated with an inversion segregating in natural populations. We sampled chromosomes from 751 mosquitoes of the malaria vector Anopheles funestus along a 1421 km transect in Cameroon that traverses savannah, highland, and rainforest ecological zones. We then developed a series of population genetic models that account for selection, migration, and assortative mating, and fit the models to the data using likelihood. Results from the best-fit models suggest there is strong local adaptation, with relative viabilities of homozygotes ranging from 25% to 130% compared to heterozygotes. Viabilities vary qualitatively between regions: the inversion is underdominant in the savannah, while in the highlands it is overdominant. The inversion is also implicated in strong assortative mating. In the savannah, the two homozygote forms show 92% reproductive isolation, suggesting that this one inversion can generate most of the genetic barriers needed for speciation.
dc.relation.haspart doi:10.5061/dryad.k94p3/1
dc.relation.haspart doi:10.5061/dryad.k94p3/2
dc.relation.isreferencedby doi:10.1111/j.1558-5646.2012.01836.x
dc.relation.isreferencedby PMID:23550747
dc.subject Chromosomal Evolution
dc.subject Population Genetics
dc.subject Chromosome inversions
dc.subject karyotype data
dc.title Data from: Reproductive isolation and local adaptation quantified for a chromosome inversion in a malaria mosquito
dc.type Article *
dwc.ScientificName Anopheles funestus
dc.contributor.correspondingAuthor Guerrero, Rafael F.
prism.publicationName Evolution

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Title KaryotypeCounts
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Description Field data. Number of Anopheles funestus collected in populations of Cameroon, by the type of arrangement in3Ra. Columns are: The name of the village, Longitude and Latitude (in WGS84 UTM Zone 33 North), the distance in km from the start of the transect, the counts of Standard homozygotes (SS), Heterozygotes (SI), and Inverted Homozygotes (II), and the total of individuals collected
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